Veranstaltung
| Titel | Ecotoxicogenomics |
| Title | Ecotoxicogenomics |
| Schwerpunkt/Focus | |
| Sprache/Language | optional |
| VV-Nr./Course No. | 134282 |
| Modulverantwortlich/Responsible | Dr. Sebastian Eilebrecht |
| Vertreter/Co-responsible | Dr. Steve Ayobahan |
| Anbieter/Teachers | Dr. Sebastian Eilebrecht |
| Typ/Type | lecture, seminars, literature work, (practical course) |
| SWS/Semerster periods per week | |
| Arbeitslast(h)/Work load | 300 |
| KP/Credit points | 10 KP |
| Zuordnung/Classification | Vertiefungs-Modul |
| Semester/Semester | WiSe |
| Studierende/Students | BSc Biowissenschaften |
| Corona-Informationen/Corona-Information | Based on the current state at the time point of the module, practical courses may be replaced by video presentations of experimental workflows and online seminars. |
| Zeit/Date | Block II: 08.01.2024 – 01.03.2024 |
| Ort/Location | Fraunhofer Institut für Molekularbiologie und Angewandte Ökologie IME, Auf dem Aberg 1, 57392 Schmallenberg (4 weeks, practical part) and online (4 weeks, theoretical part) |
| Beginn/Start | 08.01.2024 |
| Vorbesprechung/Obligatory pre-meeting | n.V. |
| Voraussetzung/Prerequisite | |
| Anmeldung/Registration | Online-Anmeldung |
| Leistungskontrollen/Performance assessments | oral presentation |
| Termine f. Leistungskontrollen/Date for performance assessments | n.A. |
| max. NP/Max. grade points | 200 NP |
| Ziele/Aims | Students will learn about approaches for ecotoxicological hazard and risk assessment at the genome scale. |
| Inhalte/Content | The module will introduce the field of ecotoxicogenomics for environmental hazard and risk assessment. Utilizing different aquatic model organisms, a focus will be put on transcriptomics and proteomics approaches for studying molecular effects induced by chemical stressors. |
| Methoden/Methods | While focusing on online lectures and seminars for introducing the topic, the course will include molecular biology methods of sample preparation and quality assessment as well as the work with data analysis pipelines. |
| Berufsrelevante und interdisziplinäre Komponenten/Occupational and interdisciplinary skills | |
| Voraussetzung für/Prerequisite for | |
| Präsenzpflicht/Compulsory presence | yes |
| Plätze/Number of participants | 5 |
| Gruppengröße/Group size | 5 |
| Materialien/Materials | Computer, ideally (but not compulsory) an R environment |
| Literatur/Literature | Reinwald, Hannes, et al. "Toxicogenomic fin (ger) prints for thyroid disruption AOP refinement and biomarker identification in zebrafish embryos." Science of The Total Environment 760 (2021): 143914. Reinwald, Hannes, et al. "Toxicogenomic profiling after sublethal exposure to nerve-and muscle-targeting insecticides reveals cardiac and neuronal developmental effects in zebrafish embryos." Chemosphere 291 (2022): 132746. Loll, Alexandra, et al. "Short-Term Test for Toxicogenomic Analysis of Ecotoxic Modes of Action in Lemna minor." Environmental Science & Technology 56.16 (2022): 11504-11515. Essfeld, Fabian, et al. "Transcriptomic profiling of clobetasol propionate-induced immunosuppression in challenged zebrafish embryos." Ecotoxicology and Environmental Safety 233 (2022): 113346. Pfaff, Julia, et al. "Toxicogenomic differentiation of functional responses to fipronil and imidacloprid in Daphnia magna." Aquatic Toxicology 238 (2021): 105927. |
| Links | https://www.ime.fraunhofer.de/en/Research_Divisions/Division_AE/Environmental_Risk_Assessment_of_Chemicals/Attract_Eco_n_OMICs_E.html |
| Sonstiges/Further information | The practical part of the course will take place at Fraunhofer IME in Schmallenberg (externally). |
Modulelemente:
Elemente of the module:
| Titel/Title | Zeit (von...bis)/Time (from...to) | Ort(Raum)/Location | |
|---|---|---|---|
| Übungen/Practical exercises | |||
| Vorlesung/Lecture | |||
| Seminare/Semeinars | |||
| Exkursionen/Excursions |
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