Veranstaltung
| Titel | Multiscale Molecular Imaging, Teil I und II |
| Title | Multiscale Molecular Imaging, Part I and II |
| Schwerpunkt/Focus | |
| Sprache/Language | englisch |
| VV-Nr./Course No. | 134140/ 134141 |
| Modulverantwortlich/Responsible | Prof. Dr. Friedemann Kiefer |
| Vertreter/Co-responsible | |
| Anbieter/Teachers | Dr. Andreas Faust, Dr. Sven Hermann, Prof. Dr. F. Kiefer, Prof. Dr. Klaus Schäfers, |
| Typ/Type | Lecture, seminar and practical laboratory course |
| SWS/Semerster periods per week | |
| Arbeitslast(h)/Work load | 2 * 150 |
| KP/Credit points | 2 * 5 |
| Zuordnung/Classification | Fortgeschrittenen-Modul |
| Semester/Semester | WiSe |
| Studierende/Students | MSc Biowissenschaften MSc Biotechnologie MSc Molekulare Biomedizin |
| Corona-Informationen/Corona-Information | Lectures and seminars will be offered "on site" unless impossible due to Corona restrictions then "online". |
| Zeit/Date | 17.10.2023 - 30.01.2024 |
| Ort/Location | Lecture theatre MIC, Röntgenstraße 16 |
| Beginn/Start | 17.10.2023 |
| Vorbesprechung/Obligatory pre-meeting | 17.10.2023 18:00 |
| Voraussetzung/Prerequisite | basic knowledge in imaging technologies |
| Anmeldung/Registration | Nur über Dozentenplätze |
| Leistungskontrollen/Performance assessments | Seminar, presentation |
| Termine f. Leistungskontrollen/Date for performance assessments | Seminar at the third date of each lecture block, 07.11. / 28.11. / 19.12. / 23.01., short präsentation at the end of the laboratory course |
| max. NP/Max. grade points | 200 |
| Ziele/Aims | The course will provide a solid understanding in the technical aspects of multiscale molecular imaging including the principles of biorthogonal chemistry and probe generation, probe pharmacology, different microscopic imaging modalities and the basis if preclinical and clinical imaging, and image reconstruction and evaluation methods. |
| Inhalte/Content | Introduction into: - the theory of advanced light (confocal, multiphoton and light-sheet) microscopy including volume imaging of tissue, - nuclear medicine and radiobiology, radiation and laser use, - the application biorthogonal organic-chemistry, probe chemistry and pharmacodynamics, - preclinical and clinical imaging and image reconstruction. For each of the four topics, microscopy, nuclear imaging, probe chemistry and medical / preclinical imaging, the theoretical background will be covered in one double lecture, applications will be illustrated by presentation of current research applications from the fields of vascular and inflammatory research in the second double lecture and current research examples will be presented and discussed in a seminar series that covers the third double hour devoted to the topic. |
| Methoden/Methods | Practical laboratory course in block V. In the practical laboratory course probe preparation and labelling of samples for imaging methods including confocal and light sheet microscopy, positron emission tomography and nuclear magnetic resonance imaging, optical tissue clearing and image evaluation will be practised in micro groups. |
| Berufsrelevante und interdisziplinäre Komponenten/Occupational and interdisciplinary skills | The importance of multiscale imaging is highlighted form the angles of biological and medical sciences. Active exchange between participants for mthe different faculaties is fostered. |
| Voraussetzung für/Prerequisite for | |
| Präsenzpflicht/Compulsory presence | yes |
| Plätze/Number of participants | maximally 8 places for the practical laboratory course, additional participants welcome for the lectures / seminars |
| Gruppengröße/Group size | Microgroups of 2 participants |
| Materialien/Materials | |
| Literatur/Literature | Up-to-date literature covering backround as well as the seminar series will be presented at the introductory lecture. |
| Links | https://www.uni-muenster.de/CRC-inSight/de/ https://www.uni-muenster.de/Cells-in-Motion/de/about/multiscale-imaging-centre.html |
| Sonstiges/Further information | Part I and II must be attended together. |
Modulelemente:
Elemente of the module:
| Titel/Title | Zeit (von...bis)/Time (from...to) | Ort(Raum)/Location | |
|---|---|---|---|
| Übungen/Practical exercises | Multiscale imaging | Practical laboratory course in block V, to be individually arranged with the supervisors. | Laboratories of the lecturers, pending on availability of the MIC building. |
| Vorlesung/Lecture | I. From microscopy to optical imaging in biomedicine II. Nuclear medicine, computation and visualization in multiscale imaging III. Chemical Biology and probe chemistry IV. Pre-clinial and diagnostic whole body and molecular imaging |
Tuesday, 18:15 - 20:15 | Lecture theatre MIC, Röntgenstraße 16 |
| Seminare/Semeinars | I. From microscopy to optical imaging in biomedicine II. Nuclear medicine, computation and visualization in multiscale imaging III. Chemical Biology and probe chemistry IV. Pre-clinial and diagnostic whole body and molecular imaging |
Tuesday, 18:15 - 20:15 | Lecture theatre MIC, Röntgenstraße 16 |
| Exkursionen/Excursions |
= Modul gehört zum SPP Imoplant / Module is part of the SSP Imoplant
= Modul gehört zum SPP Evolution /Module is part of the SSP Evolution
= Modul gehört zum SPP Bioanalytics and Biochemistry /Module is part of the SSP Bioanalytics and Biochemistry
= Modul gehört zum SPP Neuroscience and Behaviour /Module is part of the SSP Neuroscience and Behaviour
= Modul gehört zum SPP Quantitative Cell Biology /Module is part of the SSP Quantitative Cell Biology